This tool is a work in progress and any suggestions would be greatly appreciated. I will strive to reduce this impact and to ensure the high quality of teaching you can expect from the University of Jena. I look forward to meeting you â online and in person. Er koordiniert die Einsätze dieser Freiwilligen mit medizinischer Ausbildung. SARS-CoV-2 genome browser and related resources, including the following data: Like for all Ensembl data, no restrictions on the use of the COVID-19 resources are placed. Through a review of the most relevant scientific literature, and considering different levels of experimental evidence, over 150 compounds have been identified that are potentially active against COVID-19. The corona pandemic is fundamentally changing the everyday life of many people â this naturally also affects students. Designed using Hoot Business. [�{�I�)�$ ʚ3;tA!paTB�>XZL���z��P� ]� ��T�ˀ�{���� �6ׂcPYp�C �ǘ���Ys4*8��d�¦��B�֚S�1ơĴ��3`���TCDy�U^@�:�Y�x�ЁZ�����h�ᅌ0�yf���I��v�l���7��t�O��ȌJ�����W��q�i\� "�ʈ_'��DQ�@C�D��sbC���|��Sj�W`ƀC�Z*�E��w̚r�� "Bc�.��K��'�(hF�Eޔ���Fk��5����AGg�ӷ!Fiz��ʺ�Ԇ{�k���i�8 �oSS|\�@� �A�i�\�C�nh�D��Ê�\�I=���= 2m|��P������u�ɍ����mp+25�yR*�$?%T�gX�;ɲ>Snʖ&�k�V��o:yY�I�m��l��i+k wo�k���ך@M��5��Si� 0n���t��.u��xԥP�szi dr+���e��o2SV�$�&5b�0��b�[��*�^C�3~���h`R��/��� �;�D>��_���+��Y7�C=���;��� �u�mXr���ң�*��h�\�&�$�LݰҶf�c�˱k+譱l��|?�~�dS� BEAST 2 includes a graphical user-interface for setting up standard analyses and a suit of programs for analysing the results. CoVex is a unique online network and systems medicine platform for data analysis that integrates virus-human interactions for SARS-CoV-2 and SARS-CoV-1. Die Browser-basierte Lösun Vigor4 uses the VIGOR_DB project which currently has databases for the following viruses: Influenza (A & B for human, avian, and swine, and C for human), West Nile Virus, Zika Virus, Chikungunya Virus, Eastern Equine Encephalitis Virus, Respiratory Syncytial Virus, Rotavirus, Enterovirus, Lassa Mammarenavirus. The viral sequences are regularly extracted from the NCBI BLAST database and the metadata is retrieved from the associated INSDC entries. Please note: Due to the Corona crisis DFN-web conferencing tools are currently frequently used. Lectures during Corona. International Organizations and Crisis Management - IOCM in short - is the masters degree in political science of the Chair for International Relations at the Friedrich-Schiller-University Jena. The Data Portal brings together and continuously updates the relevant COVID-19 datasets and tools. Please also have a look at our general list of virus bioinformatics tools. The ELM resource offers a collection of short linear motifs that mediate interactions crucial in both native cell regulation and pathogenic interference. Explore the virus-host interactome. The Lecture Hall Management section will support you in complying with the protection regulations. This can capture longer and more specialized disordered interaction regions complementing linear motifs captured by ELM. This also applies to the exams. VADR (Viral Annotation DefineR) validates and annotates viral sequences in GenBank submissions. CORDITE (CORona Drug InTEractions database) collects and aggregates data from PubMed, MedRxiv, BioRxiv, and ChemRxiv for SARS-CoV-2. RNAcentral has launched a new tool to help scientists studying Coronaviruses to search thousands of viral genomes and explore results by virus, host, country, and more. The Coronavirus typing tool is designed to use Blast and phylogenetic methods in order to identify the Coronavirus types and genotypes of a nucleotide sequence. It collects and provides up-to-date information on computational predictions, in vitro, as well as in vivo study data. ��%����SIG�{ ��jx���A���l���-���8%�ES�kk`�,�-�$�B�Tm{����L̃��xS�SEV��*e�.�Jlۄ����ֶ�"R\��V�2����1�Z�L��V�I��d��Z�Lʲ]Ȕض�i�9����) Corona virus: Availability and Restrictions at Graduate Academy. For example, it is possible to search for a fragment of a SARS-CoV-2 genome, select similar sequences identified in COVID-19 patients, and browse sequence variants from different countries. Public life had largely come to a standstill. uni-assist has already taken comprehensive protective measures for the staff in its Berlin office. Oral examinations in the context of doctoral and habilitation procedures (disputations, colloquia, scientific lectures and talks) are currently not to be held. Medizin-Studierende oder Personen mit medizinischer Vorbildung, die sich engagieren möchten, können sich an Karsten Krohn vom Universitätsklinikum Jena [email protected] wenden. We are happy to answer your enquiries via our contact form. The nationwide survey "Studying in Germany in Corona Times" aims to examine the effects of the crisis on students at German universities and to shed light on the special features, challenges and opportunities of the largely digital summer semester 2020. Welcome to the Chair of International Relations at Friedrich Schiller University Jena! The Pfam profile hidden Markov model (HMM) library in combination with the HMMER software facilitates rapid search and annotation of coronaviruses and can be used to generate multiple sequence alignments that allow the identification of mutations and clusters of related sequences, particularly useful for outbreak tracking and studying the evolution of Coronaviruses. Es werden keine Daten im Hintergrund erhoben, jeder Scan-Vorgang ist für den Nutzer vollständig nachvollziehbar. Our team is mostly working online. PoSeiDon is a pipeline to detect significant positively selected sites and possible recombination events in an alignment of multiple coding sequences. DisGeNET is a discovery platform containing one of the largest publicly available collections of genes and variants associated with human diseases. We are happy to answer your enquiries via our contact form. Appropriate PCR primer pairs for DNA metabarcoding would match to a broad evolutionary range of taxa, such that we only need a few to achieve high taxonomic coverage. Sequence data are essential to design and evaluate diagnostic tests, to track and trace the ongoing outbreak, and to identify potential intervention options. Corona macht erfinderisch! Please also use the e-mail address [email protected]. Dazu wurden verschiedene Regelungen getroffen bzw. Further you can analyze the data online using sequence alignment, phylogenetic tree reconstruction, sequence variation (SNP), metadata-driven comparative analysis and BLAST. Letzter Stand: 16. The GISAID Initiative promotes the rapid sharing of data from the coronavirus causing COVID-19. It is capable of processing large libraries and is robust against mislabeled or low quality references. This is a fast-paced project with the COVID-19 Data Portal featuring relevant ⦠4Institute for Pharmaceutical Technology and Biopharmacy, Friedrich Schiller University Jena, Lessingstrasse 8, 07743 Jena. 3TrophoSYS GmbH, Botzstrasse 5, 07743 Jena. Both ELM and IUPred2A identify functional regions that are disordered and generally less conserved due to rapid evolvability, and hence their outputs complement the well conserved functional regions identified by Pfam. Rufen Sie in jedem Fall Ihren Hausarzt in Deutschland (alternativ die Hotline 116117) an. Jena, July 2-3, 2020. Due to the corona virus, Graduate Academy has to reduce some of its offers. If anything, the Corona crisis forces us to be creative about our teaching. This literature curation effort is now, Complete the online application form providing answers as directed Ensure you add relevant information to the “Application submission” section where you are asked to provide three 100-word paragraphs that cover your: scientific biography work history current research interests Upload a letter of support from your supervisor or a senior colleague, Complete the online application form Ensure you add relevant information to the “application submission” section where you are asked to provide three 100-word paragraphs that cover your: scientific biography work history current research interests Upload a letter of support from your supervisor or a senior colleague detailing reasons why you should be selected, International Virus Bioinformatics Meeting 2020, SARS-CoV-2 genome browser and related resources, Phylogeographic reconstruction using air transportation data. Last update: June 2, 2020 Due to the Corona pandemic, the courses in the current summer term 2020 and also in the upcoming winter term 2020/2021 will be online courses. Barrierefreiheit. COPASI supports models in the SBML standard and can simulate their behavior using ODEs or Gillespie’s stochastic simulation algorithm; arbitrary discrete events can be included in such simulations. the Fundamentals of Modern Optics and the Structure of Matter courses. ��$�i��D`��ATV��@������ZWʲ]��ض International organizations take action in order to prevent a further spread of the virusâwith the World Health Organization (WHO) leading the ⦠BEAST 2 is a cross-platform program for Bayesian phylogenetic analysis of molecular sequences. Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU) Thuringiaâs economy has been hit hard by the corona pandemic, plunging the state into a deep recession. It tackles the computationally expensive steps with linear runtime filters and efficient encodings. In Thuringia, the first corona cases occurred at the beginning of March, and in mid-March the first infections were also confirmed in Jena. UniProt also hosted webinars to describe the portal and publication submission system. ��K���އ�������% In response to the SARS-CoV-2 outbreak, Rfam produced a special release 14.2 that includes 10 new and 4 revised families that can be used to annotate the SARS-CoV-2 and other Coronavirus genomes with RNA families. Physik): Course takes place: Yes: Multimedia support: PDF (lecture slides), Video for the PDF (explanations of slides) Interaction: video conference, Discussion and feedback via discussion boards in Moodle (every week) Currently, it supports FMDV and SARS-Cov-2 viral sequences. We will meet the challenges head-on. The Master's programme starts in the winter semester 2020. At the same time, the DNA barcodes between primer pairs should be different to allow us to distinguish between species to improve resolution. The IUPred2A server is a biophysics-based prediction to identify intrinsically disordered protein regions (IDRs) and binding sites inside IDRs. It implements different network-based approaches for the identification of new drug targets and new repurposable drugs. This also applies if you are using rooms for the examination that are not centrally managed. COPASI is a software application for simulation and analysis of biochemical networks and their dynamics. ORCID is used as a mechanism to validate user credentials as well as recognition for contribution. Volle Transparenz. The corona pandemic is a global threat and major challenge for numerous countries. A research team from the Chair of Economic Geography at the University of Jena has been examining the severity of the consequences. We cover workflows and tools for. information on gene functions from Gene Ontology, Support for facets and keyword searches for exploring results, Explore up to 1,000 top hits (compared to 100 in BLAST), Integration with Rfam to annotate structured RNA elements. The ELM server includes an online tool for the identification of motifs in user input sequences, using context filters (based on structural information, localization, sequence complexity and conservation) to refine results. Each virus or family page gives an easy access to UniProtKB/Swiss-Prot viral protein entries. However, we are still available for you via email. And our most important services will continue: We are processing all incoming applications including your mail. With sadness, we regret to inform you that we have to cancel our 7 th pairfam international interdisciplinary conference on "Personality and relationships across the life span in Jena", July 2-3 2020, due to the evolving corona virus situation. On 20 March, the Friedrich Schiller University Jena went into emergency operation. ������4�v K�W\-�z0�d�]��� ��ӌ{u�Ē�J��a �b�;%�F*�����Ql��(�E������6ٹ����%�0:�w���ѐK!��Ժ�xi atm�5A�=5�YƝ�=M���};�J��qgMĤ\�����+������8�����.�,~|�0�;����*uh���v}�i �R��ƛ��m�ʽ���&�KD��6�,�+�3/n�P��%Bi�d�۾Go��Z�������q6���N�ŧx����Uc8��ۯ���Hf�h��_���F/Rs:Ѹ��_·��p_�6B:�g"a The new search uses nhmmer and enables the users to explore the results using facets powered by the EBI Search. Am Samstag, 9. uni-assist has already taken comprehensive protective measures for the staff in its Berlin office. Essential information concerning this matter is ⦠Covidex is an alignment-free machine learning subtyping tool for viral species, based on a random forest model trained over a kmer database. Informatik II (B.Sc. ([email protected]) in good time â one week in advance as a rule â to discuss arrangements. Bulgariaâs Corona-Drama in Three Acts. BEAST 2 uses Markov chain Monte Carlo (MCMC) to average over tree space, so that each tree is weighted proportional to its posterior probability. Predicted proteins encoded by the sequence are validated with nucleotide-to-protein alignments using BLAST. the discovery of potential drug targets and development of therapeutic strategies. It estimates rooted, time-measured phylogenies using strict or relaxed molecular clock models. The latest release (March 2020) is dedicated to helping researchers to fight against the COVID-19 pandemic and is registered as a COVID-19 fair share resource. This is a fast-paced project with the COVID-19 Data Portal featuring relevant datasets from EMBL-EBI Data Resources including the European Nucleotide Archive (ENA), UniProt, Protein Data Bank in Europe (PDBe), the Electron Microscopy Data Bank (EMDB), Expression Atlas, ChEMBL, and Europe PMC. This way users can get a fully annotated report on candidate disordered interaction sites, highlighting their relationships with Pfam domains, for any protein of interest. This includes genetic sequence and related clinical and epidemiological data to help researchers understand how viruses evolve and spread during epidemics and pandemics. "doc-in" is the online administration for doctoral procedures at the Friedrich Schiller University Jena and accompanies you through the entire PhD phase. Friedrich-Schiller-Universität Jena, Institut für Angewandte Physik (IAP), Max-Wien-Platz 1, D-07743 Jena The Welcome and Service Desk for Doctoral Candidates and Postdocs will be closed for face-to-face contacts until further notice. Beautiful, sweet-smelling, delicious apples. PriSeT has been applied to 19 SARS-CoV-2 genomes and computed 114 new primer pairs with the additional constraint that the sequences have no co-occurrences in other taxa. The release contains manual biocuration of experimentally validated physical Coronaviridae / host protein-protein interactions and is complementary to functional and in silico interactions shared by viruses.string. In the extracellular space, virions adhere to ACE2 receptors and get internalized through endocytosis. On average the observed changes would be expected to have no or minimal consequence on virus biology. DisGeNET COVID-19 data collection shows the results of applying text mining tools to the LitCovid dataset, to identify mentions of diseases, signs and symptoms. Person working on a computer Image: Glenn Carstens-Peters Despite the official case numbers of Covid-19 in Jena and Thuringia being very low (as of 23.06.2020), the coming winter semester will nevertheless take place online. You can find more information at: iocm.uni-jena.de. H���C�bTB���I1�\�Œ��g��v�H��[6v3y�-���� �2m�B��kħ��3�0ϸ��q�q�ʘ�n�Oڸ������-2ѸMΰ'Аr�|9�J���딶�k7��S���z�T�:ǔ���.e�B�+�j��9� ��]�����7UZBݮ�3�����X5����� ����,���ϻ��9uļ�����]o��#>5)p��6�������y���r����l�C��n���������?�����l?t7t���]��$k�}W8x��sS���6Ѻߦ���m¡ߖX5n�>]l�@�)�˟6J��'". Die Seite wird regelmäßig aktualisiert und erweitert. In the autumn of 1986, I got a box of apples from my uncle. They provide a continually-updated view of publicly available data alongside powerful analytic and visualization tools for use by the community. The ViPR database integrates various types of data for multiple virus families. E-Mail: Please write an email to [email protected]. Service hours of the hotline: daily 10:00 - 14:00. Ten publication submissions have been received so far, contributing to our understanding of the virus biology. Among them is the ACP auditorium, where main lectures in the M.Sc. It is based on the GLUE data-centric bioinformatics environment and provides a browsable database of amino acid replacements and coding region indels that have been observed in sequences from the pandemic. The annotation system is based on the analysis of the input nucleotide sequence using models built from curated RefSeqs. And our most important services will continue: We are processing all incoming applications including your mail. Matthias C. Kettemann The University of Jena, officially the Friedrich Schiller University Jena (German: Friedrich-Schiller-Universität Jena, abbreviated FSU, shortened form Uni Jena) is a public research university located in Jena, Thuringia, Germany.. ���n1�P�G�,�t\5t����W Qe�.f�R��L�)��#��!sߐQbs�k�+�f���Hj�"z�c��?��NT���I�O ִ� Im Krankheitsfall/wenn Symptome auftreten: wenn Sie in Jena wohnen, müssen Sie die Corona-Hotline +49 3641 492222 und das Fiebertelefon +49 3641 493333 informieren (alternativ: [email protected]). GISAID data Submitters and Curators ensure real-time data sharing of hCoV-19 remains reliable, to enable rapid progress in the understanding of the new COVID-19 disease and in the research and development of candidate medical countermeasures. 07743 Jena Telefon: Telefax: E-Mail: 0 36 41 9-431 70 0 36 41 9-431 72 [email protected] Jena, March 18, 2020 To the students and lecturers at the Faculty of Economics and Business Administration Information and Regulations Concerning the Corona Pandemic (last updated 18/03/2020) Dear Sir or Madam, Nextstrain is incorporating SARS-CoV-2 genomes as soon as they are shared and provides analyses and situation reports. The information provided is for research only and we cannot guarantee the correctness of the data. And we will overcome them, together. With great discipline we have all contributed to keep the number of sick people in Jena low. The Data Portal brings together and continuously updates the relevant COVID-19 datasets and tools. Ъn�������K����o���h��E{ׁ�rθ3��燏"`G�A] ���G�p>�vw�}��O The COVID-19 UniProt portal advances SARS-CoV-2 research by providing the latest knowledge on proteins relevant to the disease for both the virus and human host. Despite the fact that first facilities are re-opening under strict conditionshis, we ask you to learn and to work from home whenever possible and, in your personal behaviour, take into account that great efforts are still needed to contain the corona virus. �:M�l��Μق��D�;];��#�%2�T�t��z$ ��M�l�H�h���F]��*Vwb�C�GܲCE�V�q���e�!����� SD}��ٌ[:/�*F�Л��q�֙Xp�;��p�l�2�����Q/>~j�ܒcGIDP�?��u���B.S ELM and IUPred2A mutually include each other’s predictions, and both methods utilize the newest data from UniProt and Pfam. P-HIPSTer employs structural information to predict pan viral-human PPIs. ... âThe corona crisis is the epitome of a transboundary crisisâ The European COVID-19 Data Portal was launched by EMBL-EBI in conjunction with the European Commission, the European Open Science Cloud and ELIXIR, as part of the wider European COVID-19 Data Platform. Schools and daycare centres in Thuringia closed from 17 March. First Act. There may be longer waiting times. Präsidium und Senat der Friedrich-Schiller-Universität Jena haben sich zum Ziel gesetzt, alle Nachteile, die Studierenden durch Corona entstehen, auszugleichen. The tool allows a fast classification in pre-defined clusters (from the Nextstrain database). ViralZone project is handled by the virus program of SwissProt group. For the third year Bachelor Biology course âVom Molekül zu komplexen Gemeinschaften (BB3.Ö13)â at FSU Jena, PhD student Jennifer Gabriel and research group leader Nicole van Dam, Molecular Interaction Ecology designed a Corona proof âbrown bagâ practicum. the reliable analysis of sequencing data. The pipeline is designed for reproducibility and scalability in order to ensure reliable and fast data analysis of SARS-CoV2 data. Mai, findet der Hochschulinformationstag (HIT) der Universität Jena erstmals digital statt. The COVID-19 portal enables community crowdsourcing of publications via the “Add a publication” feature within any entry. Corona News. r�F�32� 9W Repurpose drugs. This heavy usage might lead to bottlenecks when it comes to setting up new meetings, or to disruptions when starting meetings. The tool allows users to highlight and prioritize the most frequent mutations in specific protein regions, and to monitor their frequency in the population over time. E-mail: [email protected] CoVPipe is a highly optimized and fully automated workflow for the reference-based reconstruction of SARS-CoV-2 genomes based on next generation amplicon sequencing data using CleanPlex SARS-CoV-2 Panel (Paragon Genomics, Hayward, CA, USA) from swab samples. It will determine Thus, the community can assist in associating new or missing publications to relevant UniProt entries. The opening page has been updated to give references to an overview of motif hijacking in viruses in general, and an application to detecting SARS-CoV-2 motif usage in host cell attachment and modulation. 5Institute for Medical Microbiology, University Hospital Jena, Am Klinikum 1, 07747 Jena. The goal is to aid epidemiological understanding and improve outbreak response. 14.3k Followers, 294 Following, 894 Posts - See Instagram photos and videos from Universität Jena (@unijena) If you wish to start a PhD at the University of Jena you have to register in the portal with your personal data. Sites that undergo positive selection can give you insights in the evolutionary history of your sequences, for example showing you important mutation hot spots, accumulated as results of virus-host arms races during evolution. Corona cannot fail but impact our classes, as it has impacted our lives. Increase of test capacities for suspected corona cases Researchers at the Friedrich Schiller University of Jena and the University Hospital Jena find an alternative to scarce buffer solutions when testing for the novel corona virus. PriSeT finds a primer set P balancing both: high taxonomic coverage and high resolution. Nextstrain is an open-source project to harness the scientific and public health potential of pathogen genome data. COVID-19 UniProt portal provides early pre-release access to (i) SARS-CoV-2 annotated protein sequences, (ii) closest SARS proteins from SARS 2003, (iii) human proteins relevant to the biology of viral infection, like receptors and enzymes, (iv) ProtVista visualisation of sequence features for each protein, (v) links to sequence analysis tools, (vi) access to collated community-contributed publications relevant to COVID-19, as well as (vii) links to relevant resources. CoV-GLUE is an online web application for the interpretation and analysis of SARS-CoV-2 virus genome sequences, with a focus on amino acid sequence variation. � �]{s�F��ۮ�w���Yr�|ʒE�ϖ��[��=)��Km��� ��3R��~���A"H�q��� ������|�7ή���̵�>q��;���j����3�w�k6�pay��9�˥J�;��^��bԆ��4�:貏!_�;��5�uW�T�ݸ�٭���5�R1=���m�E'��S$�LY���/�4eS*~�VK!m�IY)�BW���n�΄�eY!��� F���y�`H���ã�r �-!u�h�m0���b]s�p�kNݮ�����N�)�������|���xw>>��T�vɇ�/���vO��RL�ո#�cW���O�ݩ.��`e��*}�~�.� �sen��M�$W\���O���5�=΄��=[��(�8Z�)�wG�P���hKu��/��B���{�|ڳY�2���wKt�=�ܻ����T|�1��>��w\��]Z ViralZone is a web-resource from the Swiss Institute of Bioinformatics for all viral genus and families, providing general molecular and epidemiological information, along with virion and genome figures.
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